Biocompatible intraocular implants include a tyrosine kinase inhibitor and a biodegradable polymer that is effective to facilitate release of the tyrosine kinase inhibitor into the vitreous of an eye for an extended period of time. The therapeutic agents of the implants may be associated with a biodegradable polymer matrix, such as a matrix that is substantially free of a polyvinyl alcohol. The implants can be placed in an eye to treat or reduce the occurrence of one or more ocular conditions, such as posterior ocular conditions.本發明係關於生物相容性眼內植入物,其包括酪胺酸激酶抑制劑及生物可分解之聚合物,該聚合物在延長時期內有效促進酪胺酸激酶抑制劑之釋放至眼睛玻璃體中。該等植入物之治療劑可與生物可分解之聚合物基質相關,諸如與大體上不含聚乙烯醇之基質相關。該等植入物可置於眼睛中以治療或減輕一或多種眼睛病症(諸如後部眼睛病症)之發生。
