4-PYRAZOLYL-N-ARYLPYRIMIDIN-2-AMINES AND 4-PYRAZOLYL-N-HETEROARYLPYRIMIDIN-2-AMINES AS JANUS KINASE INHIBITORS

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专利权人:

发明人:

LI YUN LONG,YAO WENQING,RODGERS JAMES D

申请号：

IN1866/KOLNP/2010

公开号：

IN281540B

申请日:

2010.05.24

申请国别(地区):

IN

年份:

2017

代理人:

摘要：

The present invention provides substituted bicyclic heteroaryl compounds, 5 including, for example, 4-pyrazolyl-N-arylpyrimidin-2-amines and 4-pyrazolyl-N-heteroarylpyrimidin-2-amines that modulate the activity of kinases and are useful in the treatment of diseases related to activity of kinases including, for example, immune-related diseases, skin disorders, myeloid proliferative disorders, cancer, and other diseases formule :(1)

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