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SUBSTITUTED QUINAZOLINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
专利权人:
WYETH HOLDINGS CORPORATION; MADISON
发明人:
WISSNER, ALLAN,JOHNSON, BERNARD DEAN,HAMANN, PHILIP ROSS,ZHANG, NAN
申请号:
HU0002893
公开号:
HU228305B1
申请日:
1998.07.29
申请国别(地区):
HU
年份:
2013
代理人:
摘要:
This invention provides compounds of formula (1) wherein X is C3-7 cycloalkyl, pyridinyl, pyrimidinyl or phenyl ring optionally substituted as described in claim 1, R1, R3 and R4 are chosen from the groups listed in claim 1. R2 is chosen from various unsaturated acyl groups listed in claim 1, with certain compounds being disclaimed. Use as tyrosine kinase inhibitors for the treatment of cancer and certain kidney diseases such as polycystic kidney disease.
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http://www.ckcest.cn/home/

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