Ashok Bhandari,Dinesh V. Patel,Genet Zemede,Larry C. Mattheakis,David Liu
申请号:
US15046325
公开号:
US09518091B2
申请日:
2016.02.17
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The invention relates to peptide dimer compounds and peptide monomer compounds that potently inhibit binding of α4β7 to the mucosal addressin cell adhesion molecule (MAdCAM) in vivo, possess high selectivity against α4β1 binding, and have high stability under gastrointestinal conditions.