JUNGBLUT, PETER,KAUFMANN, STEFAN H. E.,SCHAIBLE, ULRICH,MOLLENKOPF, HANS,RAUPACH, BARBEL,ZIMNY-ARNDT, URSULA,LAMER, STEPHANIE,MATTOW, JENS
申请号：
CA2361246
公开号：
CA2361246C
申请日:
2000.01.28
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
The present invention relates to compositions useful in immunization againstpathogenic organisms of the genus Mycobacterium and for diagnostic purposes.In particular, the present invention relates to a composition comprising atleast one protein which is differentially expressed in a virulent strain ascompared to an avirulent strain of Mycobacteria. Furthermore, the inventionrelates to compositions comprising fusion proteins, antigenic fragments,nucleic acid molecules encoding the aforementioned proteinaceous compoundsand/or antibodies thereto. Additionally, the invention relates topharmaceutical and diagnostic compositions comprising or employing compoundsof the invention. In addition, the present invention relates to the use of thecompounds of the invention for the treatment of Mycobacterium induced diseasesand/or for the preparation of a vaccine for vaccination against Mycobacteriuminduced diseases.
