The present invention relates to novel recombinant fusion proteins, such as human antibody-based molecules called Vaccibodies, which are able to trigger both a T cell- and B cell immune response. The present invention also relates to a method of treating a cancer or an infectious disease by means of these specific fusion proteins.本発明は、新規組換え融合タンパク質、例えば、ワクシボディと呼ばれる、T細胞免疫応答及びB細胞免疫応答双方を引き起こすことが可能なヒト抗体に基づく分子等に関する。本発明はまた、これらの特異的融合タンパク質による癌又は感染症の治療方法に関する。【選択図】図1