THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS;THE TEXAS A&；M UNIVERSITY SYSTEM
发明人:
Lisa Bielke,Sherryll Layton,Billy Hargis,Neil R. Pumford,Olivia B. Faulkner,Luc Berghman,Daad Abi-Ghanem
申请号：
US16531893
公开号：
US20190351042A1
申请日:
2019.08.05
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Vaccine vectors capable of eliciting an immune response to enteric bacteria and methods of using the same are provided. The vaccine vectors include a polynucleotide encoding a PAL polypeptide. The PAL polypeptide may be expressed on the surface of the vaccine vector. The vaccine vector may also include a second polypeptide encoding an immunostimulatory polypeptide such as a CD154 polypeptide or an HMGB1 polypeptide.
