Eric Vangrevelinghe;Marc Gerspacher;Philipp Holzer;Pascal Furet;Carole Pissot Sondermann;Christoph Gaul
发明人:
Marc Gerspacher,Pascal Furet,Eric Vangrevelinghe,Carole Pissot Sondermann,Christoph Gaul,Philipp Holzer
申请号：
US12663698
公开号：
US08193189B2
申请日:
2008.06.06
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates to quinoxaline compound of the formula (I):whereinR1 is carbocyclyl or heterocyclyl, either of which is optionally substituted with 1, 2, 3, 4 or 5 R7；R2 is carbocyclyl or heterocyclyl, either of which is optionally substituted with 1, 2, 3, 4 or 5 R8；R3, R4, R5 and R6 are each independently hydrogen or R9； andR7, R8 and R9 are each independently selected from organic and inorganic substituents, their use in therapy of diseases, in particular diseases mediated by the tyrosine kinase activity of Janus kinases, including JAK-2 and JAK-3 kinases.
