The present disclosure illustrates a protective sleeve for a syringe. The protective sleeve includes a hollow pipe body and an outer sleeve. The pipe body includes a channel passing therethrough axially, and a connection part formed at a side thereof and configured to combine with the preset syringe. The outer sleeve is movably and extendably mounted on the pipe body. A hollow body of the outer sleeve includes a through hole passing through axially and configured for insertion of the pipe body, and a covering part formed at an end thereof. After the syringe is injected already, the outer sleeve can be extended outwardly to make the covering part completely cover a needle of the syringe, thereby preventing the needle from being exposed out of the outer sleeve to stab person. As a result, the protective sleeve of the present can improve safety in using syringe.