A wire-driven manipulator includes a first member and a second member into both of which a flexible member is inserted, the second member being disposed more on a base end side than the first member, wherein the first and the second members are bent by a drive of the flexible member, wherein the first member includes a bonding portion mechanically bonded with the member, wherein the second member is independent of the first member and the member, and wherein a variation of an average curvature of the first member caused by a drive of the members is larger than a variation of an average curvature of the second member.