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TRPA1 ANTAGONISTS FOR TREATMENT OF DRY EYE, OCULAR PAIN AND INFLAMMATION
专利权人:
ALGOMEDIX; INC.
发明人:
Jeffrey M. HERZ,Edward A. KESICKI,Charles P. ZUTA
申请号:
US16315113
公开号:
US20200179357A1
申请日:
2017.07.06
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Stable, clear, ophthalmic formulations and methods of use for an opthalmologically therapeutic effective amount of a TRPA1 antagonist, the formulation comprising buffer system, a viscosity enhancing agent, optionally a preservative, with an opthalmologically acceptable osmolarity and pH, all in an aqueous vehicle. These formulations are effective for treating ocular diseases or conditions caused by, or associated with, or accompanied by ocular pain and inflammatory processes, including, among others, dry eye N disease, uveitis, or any trauma caused by eye surgery or eye injury.
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