КОНСЕХО СУПЕРИОР ДЕ ИНВЕСТИГАСИОНЕС СЬЕНТИФИКАС (КСИС);УНИВЕРСИДАД ПУБЛИКА ДЕ НАВАРРА
发明人:
Грильо Дольсет, Мария Хесус,Сан Роман Аберастури, Беатрис,Паласиос Чавес, Лейре,Мена Буэно, Сара,Сабальса Барангва, Ана
申请号:
EA202091308
公开号:
EA202091308A1
申请日:
2018.11.26
申请国别(地区):
EA
年份:
2020
代理人:
摘要:
The present application provides a modified Brucella strain, its use as a medicament, and its use as a medicament for the treatment and/or prevention of brucellosis. The Brucella strain has been modified through an inactivation of the wzm gene. Further, the present application provides a pharmaceutical composition which comprises the modified Brucella strain, its use as a medicament, and its use as a medicament for the treatment and/or prevention of brucellosis. The present application also provides a kit which comprises the modified Brucella strain and a pharmaceutically acceptable carrier or diluent and its use for the treatment and/or prevention of brucellosis.