BROWN UNIVERSITY;WOMEN & INFANTS' HOSPITAL OF RHODE ISLAND
发明人:
Surendra Sharma,Satyan Kalkunte,Udo Jeschke
申请号:
US14438033
公开号:
US20150293129A1
申请日:
2013.10.28
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Disclosed herein is a method of of identifying and/or addressing incipient preeclampsia in a patient-subject by the steps of by the steps of (a) performing a bioassay to determine the level of at least one sialyl Lewis antigen in a said patient- subject at about 25 weeks of pregnancy or earlier; (b) performing a bioassay to determine the level of at least one sialyl Lewis antigen in a pregnant non-preeclampsia one or more subjects at about 30 weeks of pregnancy or later, wherein said at least one sialyl Lewis antigen assay is for a sialyl Lewis antigen assayed in step (a) is and if more than one subject is assayed, averaging said results; and (c) managing said patient-subject for preeclampsia, if said level of at least one sialyl Lewis antigen of step (a) is at or greater than about 20% above the level of such silalyl Lewis antigen assayed in step (b).