Johan Oslob,Robert Anderson,Danielle Aubele,Marc Evanchik,Jonathan Charles Fox,Brian Kane,Robert McDowell,Hector Rodriguez,Yonghong Song,Arvinder Sran
申请号:
US14309414
公开号:
US20140378491A1
申请日:
2014.06.19
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention provides novel cycloalkyl-substituted pyrimidine dione compounds that are useful for the treatment of hypertrophic cardiomyopathy (HCM) and conditions associated with left ventricular hypertrophy or diastolic dysfunction. The synthesis and characterization of the compounds is described, as well as methods for treating HCM and other forms of heart disease.