JOHAN OSLOB,Robert Anderson,Danielle Aubele,Marc Evanchik,Jonathan Charles Fox,Brian Kane,Puping Lu,Robert McDowell,Hector Rodriguez,Yonghong Song,Arvinder Sran
申请号：
US15897549
公开号：
US20180311242A1
申请日:
2018.02.15
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Provided are novel pyrimidine dione compounds and pharmaceutically acceptable salts thereof, that are useful for the treatment of hypertrophic cardiomyopathy (HCM) and conditions associated with left ventricular hypertrophy or diastolic dysfunction. The synthesis and characterization of the compounds and pharmaceutically acceptable salts thereof, are described, as well as methods for treating HCM and other forms of heart disease.
