The invention discloses a kind of cell-targeting nano-material and biomedical applications. The magnetic Nano material, which can have in the histocyte on high surface with specificity with Human Placental Ferritin Receptor, expresses, and can enter cell. Material of the invention can have the expression of high Human Placental Ferritin Receptor with specificity with wide spectrum histocyte, and efficient cell targeting can be made in animal model. The material can be used as magnetic resonance imaging contrast and fluorescent molecular probe for medical diagnosis on disease and the drug disease treatment of vector.