LONN Hans Roland,CONNOLLY Stephen,SWALLOW Steven,KARLSSON Staffan PO,AURELL Carl-Johan,PONTEN John Fritiof,DOYLE Kevin James,VAN DE POEL Amanda Jane,JONES Graham Peter,WATSON David Wyn,MACRITCHIE Jaqu,PONTEN
申请号:
SI201530170
公开号:
SI3097086T1
申请日:
2015.01.23
申请国别(地区):
SI
年份:
2018
代理人:
摘要:
The present disclosure relates to certain (2 S )- N -[(1 S )-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamide compounds (including pharmaceutically acceptable salts thereof), that inhibit dipeptidyl peptidase 1 (DPP1) activity, to their utility in treating and/or preventing clinical conditions including respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), to their use in therapy, to pharmaceutical compositions containing them and to processes for preparing such compounds.