Hans Roland LONN,Stephen CONNOLLY,Steven SWALLOW,Staffan PO KARLSSON,Carl-Johan AURELL,John Fritiof PONTÉN,Kevin James DOYLE,Amanda Jane VAN DE POËL,Graham Peter JONES,David Wyn WATSON,Jaqueline Anne
申请号:
US14601371
公开号:
US20150210655A1
申请日:
2015.01.21
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present disclosure relates to certain (2S)-N-[(1S)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamide compounds (including pharmaceutically acceptable salts thereof),that inhibit dipeptidyl peptidase 1 (DPP1) activity, to their utility in treating and/or preventing clinical conditions including respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), to their use in therapy, to pharmaceutical compositions containing them and to processes for preparing such compounds.