DAVIES, JULIAN,MAGRINI, FABIO,MARTIN, ANDREA PAULA,MOZAFFARIAN, NEELUFAR,PATEL, CHETANKUMAR NATVARLAL,SCHROEDER, OLIVER
申请号:
CA2939543
公开号:
CA2939543C
申请日:
2015.03.13
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The invention relates to engineered, humanized antibodies that have high binding affinity for and neutralize human IL-21, methods of using the antibodies to treat conditions in which antagonism or neutralization of the effects of IL-21 is warranted, such as autoimmune conditions, compositions and methods for recombinantly producing the antibodies, and pharmaceutical compositions comprising the antibodies.