Julian Davies,Fabio Magrini,Andrea Paula Martin,Neelufar Mozaffarian,Chetankumar N. Patel,Oliver Schroeder
申请号:
US14657075
公开号:
US09394362B2
申请日:
2015.03.13
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The invention relates to engineered, humanized antibodies that have high binding affinity for and neutralize human IL-21, methods of using the antibodies to treat conditions in which antagonism or neutralization of the effects of IL-21 is warranted, such as autoimmune conditions, compositions and methods for recombinantly producing the antibodies, and pharmaceutical compositions comprising the antibodies.