Northwestern University;The Board of Trustees of the University of Illinois
发明人:
David J. Klumpp,Anthony J. Schaeffer,Bryan A. White
申请号:
US14677239
公开号:
US09783858B2
申请日:
2015.04.02
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Provided herein are kits, compositions, and methods for diagnosing and treating interstitial cystitis (IC) and/or interstitial cystitis/bladder pain syndrome (IC/BPS) based on finding lower levels of certain bacteria in a subject's stool sample (e.g., O. splanchnicus, F. prausnitzii, C. aerofaciens, E. sinensis, L. longoviformis, and R. intestinalis). In certain embodiments, then present invention provides probiotic formulations containing live bacteria (e.g., from O. splanchnicus, F. prausnitzii, C. aerofaciens, E. sinensis, L. longoviformis, and R. intestinalis).