Northwestern University;The Board of Trustees of the University of Illinois
发明人:
David J. Klumpp,Anthony J. Schaeffer,Bryan A. White
申请号:
US16436443
公开号:
US20190360024A1
申请日:
2019.06.10
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Provided herein are kits, compositions, and methods for diagnosing and treating interstitial cystitis (IC) and/or interstitial cystitis/bladder pain syndrome (IC/BPS) based on finding lower levels of certain bacteria in a subject's stool sample (e.g., O. splanchnicus, F. prausnitzii, C. aerofaciens, E. sinensis, L. longoviformis, and R. intestinalis). In certain embodiments, then present invention provides probiotic formulations containing live bacteria (e.g., from O. splanchnicus, F. prausnitzii, C. aerofaciens, E. sinensis, L. longoviformis, and R. intestinalis).