MACROCYCLE CONTENANT DE L'AMINOPYRAZOLE ET DE LA PYRIMIDINE, COMPOSITION PHARMACEUTIQUE ET UTILISATION DE CELUI-CI

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专利权人:

LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.;CENTAURUS BIOPHARMA CO., LTD.;CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

发明人:

DAI, LIGUANG,DUAN, XIAOWEI,YANG, YANQING,LIU, XIJIE,LI, HONGJUAN,ZHAO, NA,SUN, YINGHUI,KONG, FANSHENG,ZHANG, JIUQING,ZHU, YIZHONG,YANG, LING,LIU, FEI

申请号：

CA3071032

公开号：

CA3071032A1

申请日:

2018.08.23

申请国别(地区):

CA

年份:

2019

代理人:

摘要：

The present application relates to a macrocycle containing aminopyrazole andpyrimidine, which is represented by formula (I), a pharmaceutical compositionthereof, anda use thereof in inhibiting tropomyosin receptor kinase (Trk) activity and intreatingdiseases in mammals that are mediated by Trk.(see formula I)

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http://www.ckcest.cn/home/