MACROCYCLE CONTENANT DE L'AMINOPYRAZOLE ET DE LA PYRIMIDINE, COMPOSITION PHARMACEUTIQUE ET UTILISATION DE CELUI-CI

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专利权人:

Lianyungang Runzhong Pharmaceutical Co., Ltd.;Centaurus BioPharma Co., Ltd.;Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

发明人:

DAI, Liguang,DUAN, Xiaowei,YANG, Yanqing,LIU, Xijie,LI, Hongjuan,ZHAO, Na,SUN, Yinghui,KONG, Fansheng,ZHANG, Jiuqing,ZHU, Yizhong,YANG, Ling,LIU, Fei

申请号：

EP18849368

公开号：

EP3674307A1

申请日:

2018.08.23

申请国别(地区):

EP

年份:

2020

代理人:

摘要：

The present application relates to a macrocycle containing aminopyrazole and pyrimidine, which is represented by formula (I), a pharmaceutical composition thereof, and a use thereof in inhibiting tropomyosin receptor kinase (Trk) activity and in treating diseases in mammals that are mediated by Trk.

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http://www.ckcest.cn/home/