Prashantha Gunaga,Rajeev S. Bhide,Rajesh Onkardas Bora,Manoranjan Panda,Navnath Dnyanoba Yadav,Eldon Scott Priestley,Jeremy Richter
申请号：
US16344823
公开号：
US20190248769A1
申请日:
2017.11.02
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Disclosed are compounds of Formula (I) or a salt thereof, wherein R1 is (II) or (III)； each W is independently NR1b or O； Z is a bond or CHR1d； and R1, R2, Rd, R3, L1, L2, R1a, R1b, R1c, and n are define herein. Also disclosed are methods of using such compounds as inhibitors of ROMK, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating cardiovascular diseases.
