Indu T. BHARATHAN,Chris BLACKBURN,Jeffrey P. CIAVARRI,Jouhara CHOUITAR,Courtney A. CULLIS,Natalie D'AMORE,Paul E. FLEMING,Kenneth M. GIGSTAD,Krista E. GIPSON,Mario GIRARD,Yongbo HU,Janice LEE,Gang LI,Natalie DAMORE,M
申请号:
US15665506
公开号:
US20180118762A1
申请日:
2017.08.01
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention provides a compound of formula I:and pharmaceutically acceptable salts thereof, wherein X, R1, R2, R3, R4, R5, L1, L2, m, and n, are as described in the specification. Such compounds are inhibitors of VPS34 and thus useful for treating proliferative, inflammatory, or cardiovascular disorders.