The invention provides a mattress structure with a excreta collection device, which comprises a mattress body and a excreta collection device. Among them, the center of the mattress body is provided with a groove, and the waste collection device is arranged in the groove, and has an opening, and a baffle is arranged on the opening. In this work, a collection device is set up to solve the problem of inconveniences in cleaning the excrement of the bedridden.本創作提供了一種具有排泄物收集裝置之床墊結構,包含床墊體以及排泄物收集裝置。其中,床墊體中央設置有凹槽;而排泄物收集裝置設置於凹槽中,且具有開口,並在開口上設置有擋片。本創作藉由排泄物收集裝置之設置,解決了習知照護者在清理臥床者的排泄物時所產生的不便之問題。