A specimen-sample estimation apparatus includes: a light emitter configured to emit white light to irradiate light to a specimen sample including a living tissue; special light filters that are insertable and removable to and from an optical path of the white light, each special light filter being configured to transmit light having a different wavelength band; a driver configured to move one of the special light filters to the optical path; an imager configured to image the specimen sample to generate image data; and a processor including hardware, the processor being configured to detect a core tissue region of the living tissue appearing in an image corresponding to the image data, calculate an amount of tissue of the living tissue, based on the detected core tissue region, and determine whether the calculated amount of tissue is equal to or larger than a predetermined threshold.