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Fibrosis inhibitor
专利权人:
NIPPON SHINYAKU CO.; LTD.
发明人:
Koji Murakami,Takuya Toramoto
申请号:
US15155202
公开号:
USRE046364E1
申请日:
2016.05.16
申请国别(地区):
US
年份:
2017
代理人:
摘要:
[Object] The main object of the present invention is to provide a fibrosis inhibitor.[Solving Means] The present invention relates to a fibrosis inhibitor containing the heterocyclic derivative represented by the following general formula (1) or a pharmaceutically acceptable salt thereof as an active ingredient;In the formula (1),R1 and R2 are the same or different and each represents an optionally substituted aryl;R3 and R4 are the same or different and each represents hydrogen atom or alkyl;R5 represents hydrogen atom, alkyl or halogen atom;Y represents N or N→O;A represents NR6, and R6 represents hydrogen atom, alkyl, etc.;D represents alkylene or alkenylene which is optionally substituted with hydroxy;E represents phenylene or a single bond;G represents O, S, etc.; andQ represents carboxy, alkoxycarbonyl, etc.
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