WILLIAMS, JOHN,BZYMEK, KRZYSZTOF P.,HORNE, DAVID,XIE, JUN
申请号：
CA2981504
公开号：
CA2981504A1
申请日:
2016.03.30
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
Provided herein are functionalized monoclonal antibodies (mAbs) including antibody fragments, including those where a Fab-binding molecule (Fab binding moiety) linked to a steric hindering molecule (steric hindering chemical moiety) is mechanically interlocked (e.g., through noncovalent conjugation) with the antibody or antibody fragment. Also provided are compositions that form highly stable and versatile drug delivery and diagnostic compositions.
