WILLIAMS, John,BZYMEK, Krzysztof, P.,HORNE, David,XIE, Jun
申请号：
EP16774128
公开号：
EP3277712A4
申请日:
2016.03.30
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
Provided herein are functionalized monoclonal antibodies (mAbs) including antibody fragments, including those where a Fab-binding molecule (Fab binding moiety) linked to a steric hindering molecule (steric hindering chemical moiety) is mechanically interlocked (e.g., through noncovalent conjugation) with the antibody or antibody fragment. Also provided are compositions that form highly stable and versatile drug delivery and diagnostic compositions.
