LEE, CYNTHIA K.,MONATH, THOMAS P.,GUERTIN, PATRICK M.,HAYMAN, EDWARD G.
申请号:
CA2768866
公开号:
CA2768866C
申请日:
2011.01.25
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The invention provides a an inactive, non-replicating vaccine comprising whole virion, chemically inactivated Yellow Fever virus which is inactivated using a method that ensures preservation of critical, neutralizing epitopes. The Yellow Fever virus has been adapted to propagate in cells to higher yields than the unadapted virus. The invention also provides methods for preventing Yellow Fever viral infection.