Thomas P. Monath;Edward G. Hayman;Patrick M. Guertin;Cynthia K. Lee
发明人:
Cynthia K. Lee,Thomas P. Monath,Patrick M. Guertin,Edward G. Hayman
申请号：
US13012917
公开号：
US08741312B2
申请日:
2011.01.25
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The invention provides a an inactive, non-replicating vaccine comprising whole virion, chemically inactivated Yellow Fever virus which is inactivated using a method that ensures preservation of critical, neutralizing epitopes. The Yellow Fever virus has been adapted to propagate in cells to higher yields than the unadapted virus. The invention also provides methods for preventing Yellow Fever viral infection.
