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low oil pharmaceutical emulsion compositions comprising progestogen
专利权人:
Besins Healthcare Luxembourg Sarl
发明人:
Eva-Maria Di Hoiser,Georg Achleitner,Laura Pickersgill
申请号:
BR112012027279
公开号:
BR112012027279A2
申请日:
2011.04.26
申请国别(地区):
BR
年份:
2018
代理人:
摘要:
The invention relates to a sterile, ready-to-use, pharmaceutical oil-in water emulsion composition for parenteral administration comprising: 0.015 to 1.2% wt./vol. of progestogen; 0.5-30% wt./vol.oil, wherein the oil comprises at least 85% wt.wt. triglyceride; 0.0425-12.5% wt./vol phospholipid; 61.4-99.4% wt./vol. aqueous medium; wherein the phospholipid is present in an amount of 6.8% - 43% of the oil (wt./wt.), and wherein the progestogen is present in an amount greater than or equal to 2.1wt% of the oil, preferably greater than or equal to 2.2wt% of the oil. The invention further relates to the use of the aforementioned composition in therapeutic or prophylactic treatment, said treatment comprising intravenous administration of the pharmaceutical composition.
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