Georg Achleitner,Eva-Maria Hoiser,Laura Pickersgill
申请号：
US13916288
公开号：
US20140147474A1
申请日:
2013.06.12
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Described are a sterile, ready-to-use, pharmaceutical oil-in water emulsion compositions for parenteral administration comprising:0.015 to 1.2% wt/vol of progestogen；0.5-30% wt/vol oil, wherein the oil comprises at least 85% wt/wt triglyceride；0.0425-12.5% wt/vol phospholipid；61.4-99.4% wt/vol aqueous medium；wherein the phospholipid is present in an amount of 6.8%-43% of the oil (wt/wt), and wherein the progestogen is present in an amount greater than or equal to 2.1 wt % of the oil.Also described are methods of making such compositions and method of using such compositions in therapeutic or prophylactic treatment, such as treatments comprising intravenous administration of the pharmaceutical composition.
