PROBLEM TO BE SOLVED: To provide a method of treating a surface of an object, not only capable of imparting an antibacterial property to an object surface but also capable of removing the antibacterial property that has been imparted as well as imparting the antibacterial property again after the removal thereof.SOLUTION: The method includes a step of binding inorganic particles (silica particles 2 that expose silanol groups 3) to an object surface 1, a step of binding a protein with an antibacterial property (protamine) or basic peptides derived from the protein to the inorganic particles, and a step of turning the object surface 1 into an acidic environment with an acid solution 5 and removing the protein or basic peptides from the inorganic particles. The method also includes a step of turning the object surface 1 from which the protein or basic peptides have been removed into a neutral or alkaline environment and binding the protein or basic peptides to the inorganic particles again.COPYRIGHT: (C)2013,JPO&INPIT【課題】対象表面に抗菌性を付与できるだけでなく、一旦付与された抗菌性を除去したり、あるいは除去後再度抗菌性を付与することができる対象表面の処理方法を提供する。【解決手段】対象表面1に無機粒子(シラノール基3を露出するシリカ粒子2)を結合させる工程と、無機粒子に、抗菌性を有するタンパク(プロタミン)又はタンパクから誘導される塩基性ペプチドを結合させる工程と、対象表面1を酸性溶液5により酸性環境とし、タンパク又は塩基性ペプチドを無機粒子から除去する工程とを含む。さらに、タンパク又は塩基性ペプチドを除去した対象表面1を中性又はアルカリ性環境とし、タンパク又は塩基性ペプチドを無機粒子に再度結合させる工程とを含む。【選択図】図6
