NIALL MORRISON BARR MARTIN,GRAEME CAMERON MURRAY SMITH,STEPHEN PHILIP JACKSON,VINCENT JUNIOR M. LOH,XIAO-LING FAN COCKCROFT,IAN TIMOTHY WILLIAMS MATTHEWS,KEITH ALLAN MENEAR,FRANK KERRIGAN,ALAN ASHWORT
申请号:
IS8052
公开号:
IS2813B
申请日:
2005.09.28
申请国别(地区):
IS
年份:
2012
代理人:
摘要:
Compounds of the formula (I): wherein A and B together represent an optionally substituted, fused aromatic ring; X can be NR<;X>; or CR<;X>;R<;Y>;; if X NR<;X>; then n is 1 or 2 and if X = CR<;X>;R<;Y>; then n is 1; R<;X>; is selected from the group consisting of H, optionally substituted C1-20 alkyl, C5-20 aryl, C3-20 heterocyclyl, amido, thioamido, ester, acyl, and sulfonyl groups; R<;Y>; is selected from H, hydroxy, amino; or R<;X>; and R<;Y>; may together form a spiro-C3-7 cycloalkyl or heterocyclyl group; R<;C1>; and R<;C2>; are both hydrogen, or when X is CR<;X>; R<;Y>;, R<;C1>;, R<;C2>;, R<;X>; and R<;Y>;, together with the carbon atoms to which they are attached, may form an optionally substituted fused aromatic ring; and R<;1>; is selected from H and halo.