A container for storing a biological sample for molecular diagnostic testingand/or histological testing is provided.The container includes a first chamber for receiving a sample holder therein,a second chamber, and a closure for enclosing thecontainer. A breakable membrane, such as a piercable foil, extends within thecontainer and separates the two chambers. Whenthe breakable membrane is broken, fluid can pass between the first and secondchambers. The membrane may be broken throughan activator on the closure, such as a depressible member or a rotatablecarrier, causing the sample holder to break through themembrane.