A container for storing a biological sample for molecular diagnostic testingand/or histological testing is provided. The container includes a first chamberfor receiving a sample holder therein, a second chamber, and a closure for enclosingthe container. A breakable membrane, such as a piercable foil, extends withinthe container and separates the two chambers. When the breakable membrane isbroken, fluid can pass between the first and second chambers. The membrane maybe broken through an activator on the closure, such as a depressible member ora rotatable carrier, causing the sample holder to break through the membrane.