PUTNAM, DAVID A.,ROSENTHAL, JOSEPH,HUANG, CHUNG-JR.,DELISA, MATTHEW,MENDEZ, SUSANA
申请号:
EP13772865
公开号:
EP2833911A4
申请日:
2013.03.13
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
The present invention relates to a probiotic cell transformed with a construct suitable to overexpress and display on the surface of the probiotic cell a fusion protein comprising at least a portion of a transport protein coupled to at least a portion of one or more antigenic proteins or peptides. Probiotic-derived vesicles displaying this fusion protein as well as methods of inducing an immune response using the probiotic cells or vesicles are also disclosed.