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COMPOSITIONS COMPRISING BILE ACID SEQUESTRANTS FOR TREATING ESOPHAGEAL DISORDERS
专利权人:
INC.;IRONWOOD PHARMACEUTICALS
发明人:
CURRIE, MARK G
申请号:
NZ57820407
公开号:
NZ578204A
申请日:
2007.12.21
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed is a sustained-release pharmaceutical dosage form adapted for oral administration to a subject in need thereof, comprising a therapeutically effective amount of at least one bile acid sequestrant selected from colesevelam and colesevelam hydrochloride and a gastric-retention vehicle composition comprising one or more hydrogels, wherein said dosage form is adapted for use in preventing or treating an esophageal disorder selected from heartburn, erosive esophagitis, GERD, esophagitis, Barrett's esophagus, esophageal adenocarcinona and non-responsive GERD. Also disclosed is the use of the dosage form in the manufacture of a medicament for preventing or treating an esophageal disorder selected from heartburn, erosive esophagitis, GERD, esophagitis, Barrett's esophagus, esophageal adenocarcinona and non-responsive GERD.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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