AGARWAL, Rajesh Kumar,BETTS, III, William L.,HENSHILWOOD, James A.,KIANG, Yuan-Hon,POST, Noah
申请号：
MEP33809
公开号：
ME01090B
申请日:
2005.12.20
申请国别(地区):
ME
年份:
2012
代理人:
摘要：
The present invention is directed to methods of preparing ( R )-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride hemihydrate comprising at least partially dissolving ( R )-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride in a crystallizing solvent containing water, and inducing precipitation of the hemihydrate from the crystallizing solvent.
