Disclosed herein are processes for formulating a protein or a peptide for oral delivery, the process comprising the steps of: obtaining a powder containing the protein or peptide； obtaining an amount of an enteric polymer, wherein the enteric polymer is neutralized so that it is soluble in water； optionally obtaining at least one excipient； mixing the protein or peptide, the neutralized enteric polymer, and optionally the at least one excipient to obtain a First Dispersion； granulating the First Dispersion on a fluidized bed to obtain a Second Dispersion； whereby the protein or peptide in the Second Dispersion undergoes less than 50% proteolysis under gastric conditions.
