CHIMERIC POLYPEPTIDES, POLYNUCLEOTIDES ENCODING SAME, CELLS EXPRESSING SAME AND METHODS OF PRODUCING SAME

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专利权人:

Protalix Ltd.

发明人:

Yoseph SHAALTIEL,Uri HANANIA,Tali KIZHNER,Tami ARIEL,Svetlana GINGIS-VELITSKI

申请号：

US16045848

公开号：

US20180327476A1

申请日:

2018.07.26

申请国别(地区):

US

年份:

2018

代理人:

摘要：

A plant produced chimeric polypeptide is provided. The plant produced chimeric polypeptide comprising:(i) a first domain which comprises a TNF Alpha binding domain of a TNF receptor, and(ii) a second domain which comprises an Fc domain of an immunoglobulin, wherein the first domain and the second domain are N-terminally to C-terminally respectively sequentially translationally fused and wherein the chimeric polypeptide specifically binds TNF Alpha.

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