A method is provided for managing manual entries of blood glucose measures in relation to a structured collection procedure administered by a portable computing device. The method includes: receiving an expected time for an event associated with a structured collection procedure, defining an acceptance window for a given collection action associated with the structured collection procedure and creating a reminder for the given collection action in a persistent data store, where the reminder specifies a time at which to initiate a reminder. Upon receiving a data entry of a blood glucose measure, the reminder event is purged from the data store when the data entry is received prior to the time at which to initiate the reminder. Conversely, a reminder notification is presented to the user when the data entry has not been received in advance of the time at which to initiate the reminder.
