Urigen Pharmaceuticals, Inc.;Parsons, C. Lowell;Goldberg, Michael M.;Meenan, Christopher, P.
发明人:
申请号：
EP15751441.5
公开号：
EP3110427A4
申请日:
2015.02.24
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
The present invention is directed to a pharmaceutical composition comprising: (1) a therapeutically effective quantity of sodium pentosan polysulfate； (2) a quantity of a penetration enhancer sufficient to improve the bioavailability of the sodium pentosan polysulfate； and (3) optionally, a pharmaceutically acceptable carrier and to methods for the oral administration of sodium pentosan polysulfate with improved bioavailability for the treatment of interstitial cystitis and other urinary tract diseases and conditions. Such compositions and methods allow the administration of sodium pentosan polysulfate at lower dosages to reduce the frequency and severity of side effects.
