GOLDBERG, MICHAEL; INC.;URIGEN PHARMACEUTICALS, INC.;MEENAN, CHRISTOPHER, P.;URIGEN PHARMACEUTICALS;PARSONS, C. LOWELL
发明人:
PARSONS, C. LOWELL,GOLDBERG, MICHAEL,MEENAN, CHRISTOPHER, P.
申请号：
CA2949480
公开号：
CA2949480A1
申请日:
2015.02.24
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
The present invention is directed to a pharmaceutical composition comprising: (1 ) a therapeutically effective quantity of sodium pentosan polysulfate； (2) a quantity of a penetration enhancer sufficient to improve the bioavailability of the sodium pentosan polysulfate； and (3) optionally, a pharmaceutically acceptable carrier and to methods for the oral administration of sodium pentosan polysulfate with improved bioavailability for the treatment of interstitial cystitis and other urinary tract diseases and conditions. Such compositions and methods allow the administration of sodium pentosan polysulfate at lower dosages to reduce the frequency and severity of side effects.
