HIPSKIND, PHILIP ARTHUR,TAKAKUWA, TAKAKO,JESUDASON, CYNTHIA DARSHINI,GADSKI, ROBERT ALAN,HORNBACK, WILLIAM JOSEPH,PICKARD, RICHARD TODD,BEAVERS, LISA SELSAM
申请号:
CA2602234
公开号:
CA2602234C
申请日:
2006.03.28
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The present invention discloses novel compounds of Formula (I) orpharmaceutically acceptable salts thereof which have histamine-H3 receptorantagonist or inverse agonist activity, as well as methods and intermediatesfor preparing such compounds. In another embodiment, the invention disclosespharmaceutical compositions comprising compounds of Formula (I) as well asmethods of using these compositions to treat obesity, cognitive deficiencies,narcolepsy, and other histamine H3 receptor-related diseases.