Nicolas Lachance,Serge Leger,Renata M. Oballa,David Powell,Geoffrey K. Tranmer,Evelyn Martins,Yves Gareau
申请号：
US13255922
公开号：
US20120010186A1
申请日:
2010.03.18
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Heterocyclic compounds of structural formula I are inhibitors of stearoyl-coenzyme A delta-9 desaturase (SCD). The compounds of the present invention are useful for the prevention and treatment of conditions related to abnormal lipid synthesis and metabolism, including cardiovascular disease atherosclerosis obesity diabetes neurological disease Metabolic Syndrome insulin resistance cancer, liver steatosis and non-alcoholic steatohepatitis.
