The present invention provides the application of kalimycin and its pharmaceutically acceptable salts in the preparation of a medicament for treating tumors. The above-mentioned kalmycin and its pharmaceutically acceptable salts include breast cancer, liver cancer, lung cancer, renal cancer, brain tumor, cervical cancer, prostate cancer, pancreatic adenocarcinoma, esophageal cancer, gastric adenocarcinoma, colon cancer, lymphoma or leukemia. It has a relatively good therapeutic effect on various types of tumors, especially human breast cancer cells MCF-7 and MDA-MB-231, human hepatoma cell HepG2, human non-small cell lung cancer cell A549, human large cell lung cancer cell It has a clear inhibitory effect on the growth of H460 and H1299, human renal clear cell carcinoma cell 786-O, human renal cell carcinoma cell 769-P, human glioma cell U251 and the like. [Selection diagram] Figure 1本発明は、腫瘍を治療する薬物の調製におけるカリマイシンおよびその薬学的に許容可能な塩の応用を提供している。前記カリマイシンおよびその薬学的に許容可能な塩は、乳腺癌、肝癌、肺癌、腎癌、脳腫瘍、子宮頸癌、前立腺癌、膵臓腺癌、食道癌、胃腺癌、結腸癌、リンパ腫または白血病など数種の腫瘍に対して、比較的良好な治療効果を有し、特にヒト乳腺癌細胞ＭＣＦ－７およびＭＤＡ－ＭＢ－２３１、ヒト肝癌細胞ＨｅｐＧ２、ヒト非小細胞肺癌細胞Ａ５４９、ヒト大細胞肺癌細胞Ｈ４６０およびＨ１２９９、ヒト腎淡明細胞癌細胞７８６－Ｏ、ヒト腎細胞癌細胞７６９－Ｐ、ヒト神経膠腫細胞Ｕ２５１などの成長に対して、明らかな抑制作用を有する。【選択図】 図1
